Morpholine → HCID 51037320, compound

Participants

Reaction Conditions

Reaction Steps

To 5-benzo[1,3]dioxol-5-ylmethyl-8-fluoro-[1,2,4]triazolo[1,5-c]quinazolin-2-ylamine (0.05 g, 0.15 mmol), prepared as described in Example 21, morpholine (1 mL) was added and the mixture was heated at 140° C. for 2 h. The reaction was cooled at room temperature, the solid precipitated was filtered and washed with a mixture MeOH/H2O 9:1, to provide the title compound (0.03 g, 50% yield).

Provenance & Evidence