Methylamine → HCID 57855921, compound

Participants

Reaction Steps

See example H3 for the reaction conditions using 9-chloro-2-[2-(3-chloro-pyridin-2-yl)-5-trifluoromethyl-2H-pyrazol-3-yl]-6,7-dimethyl-3-oxa-1,5,8-triaza-anthracen-4-one as starting material and 2 equivalents of methylamine (40% in H2O). After 10 hours reaction time and purification by flash chromatography on silica gel, a white solid is obtained in 68% yield. m.p.: 221-224° C.

Provenance & Evidence