HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → HCID 57856004, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | HCID 57855984 | HCID 57855984 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 57856004 | HCID 57856004 | — |
Reaction Steps
9-Chloro-2-[2-(3-chloro-pyridin-2-yl)-5-trifluoromethyl-2H-pyrazol-3-yl]-6-trifluoromethyl-3-oxa-1,5-diaza-anthracen-4-one is reacted with methylamine in THF analogously to the procedure given in step i) of example H-18. The title product is obtained as yellow crystals after flash column chromatography eluting with 1:1 hexane:ethyl acetate. m.p.: 235-237° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08580785B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-85a77e43d361455c9aaa9329abfc809f |
| Source note | uspto-grants-2013_11 |