HCID 58961526, compound → HCID 58327737, compound

Participants

Reaction Steps

(4-((2-(2-(4-(2-Methoxyethyl)piperazin-1-yl)ethyl)phenyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-5-yl)(phenyl)methanone was synthesized using 2-(2-(4-(2-methoxyethyl)piperazin-1-yl)ethyl)aniline and (4-chloro-7H-pyrrolo[2,3-d]pyrimidin-5-yl)(phenyl)methanone according to the general procedure A. A white solid was obtained. M.p.=192-193° C.; 400 MHz 1HNMR (DMSO-d6) δ 10.66 (s, 1H), 8.31 (s, 1H), 7.98-7.94 (m, 2H), 7.84-7.82 (m, 2H), 7.70-7.66 (m, 1H), 7.60-7.57 (m, 2H), 7.30-7.25 (m, 2H), 7.13-7.09 (m, 1H), 3.33 (t, J=6.0 Hz, 4H), 3.32 (s, 3H), 2.90 (d, J=8.0 Hz, 2H), 2.51-2.46 (m, 4H), 2.36-2.33 (m, 4H), 2.24 (bs, 2H); LCMS [M+H] 463.

Provenance & Evidence