反应详情

50 mg of palladium on carbon (5%) were added to a solution of 150 mg (41%) of benzyl 3-{4-[5-(2-fluorophenoxy)oxazolo[5,4-b]pyridin-2-yl]-2,6-dimethylphenoxy}-2,2-dimethylpropionate in 7.5 ml of ethyl acetate, and the mixture was hydrogenated at 5 bar for 16 h. The catalyst was filtered off and the filtrate was concentrated. This gave 100 mg (80%) of the title compound.

1. filtrationThe catalyst was filtered off
2. concentrationthe filtrate was concentrated