HCID 66922212, compound → HCID 66922112, compound

HRID 2039854Notes

Reaction equation

HRID 2039854 reaction equation
[CH:1]1([N:7]2[C:15]3[CH:14]=[C:13]([O:16][CH3:17])[N:12]=[CH:11][C:10]=3[CH:9]=[CH:8]2)[CH2:6][CH2:5][CH2:4][CH:3]=[CH:2]1>[Pd].C(O)C>[CH:1]1([N:7]2[C:15]3[CH:14]=[C:13]([O:16][CH3:17])[N:12]=[CH:11][C:10]=3[CH:9]=[CH:8]2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

4

Reactant 1

HCID 66922212HCID 66922212, compound

Product 1

HCID 66922112HCID 66922112, compoundYield 94.6%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

The compound of step 1 (5.6 g, 24.5 mmol) and palladium on charcoal (1.12 g, 10%) were stirred in ethanol (160 ml) under a hydrogen atmosphere for 3 h. The catalyst was filtered off and the solvent removed in vacuo to give 5.34 g of the title compound.

Workup

  1. filtrationThe catalyst was filtered off
  2. customthe solvent removed in vacuo

Sources & evidence

ORD record
ord-c23e80ff739b47988f3c9e4501c4eaa0
Source dataset
uspto-grants-2013_11
Patent number
US08580813B2

Reaction notes

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