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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2039864Generated: October 31, 2026

Hydrochloric Acid → HCID 56678781, compound

https://huagongshe.com/reaction/2039864

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant2,6-DimethylphenolHCID 11335—
ReactantHCID 66922147HCID 66922147—
ReactantHCID 66922243HCID 66922243—
ProductHCID 56678781HCID 56678781—

Reaction Steps

The compound of step 7 (200 mg, 447 μmol) and 2,6-dimethylphenol were reacted analogously as described in example 1, step 6, and the product subsequently reacted as described in example 1, step 7. The obtained solid was dissolved in a small quantity of MOH, mixed with hydrochloric acid (0.1 M) and lyophilized overnight to give 32 mg of the title compound in the form of the [1-cyclohexyl-2-(2,6-dimethyl-phenoxy)-1H-pyrrolo[3,2-b]pyridin-3-yl]-piperazin-1-yl-methanone dihydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08580813B2
Source datasetuspto-grants-2013_11
ORD IDord-cb6cc6585fa140678c7f99c932eed8c2
Source noteuspto-grants-2013_11