反应详情

The compound of step 7 (200 mg, 447 μmol) and 2,6-dimethylphenol were reacted analogously as described in example 1, step 6, and the product subsequently reacted as described in example 1, step 7. The obtained solid was dissolved in a small quantity of MOH, mixed with hydrochloric acid (0.1 M) and lyophilized overnight to give 32 mg of the title compound in the form of the [1-cyclohexyl-2-(2,6-dimethyl-phenoxy)-1H-pyrrolo[3,2-b]pyridin-3-yl]-piperazin-1-yl-methanone dihydrochloride.

1. customthe product subsequently reacted
2. dissolutionThe obtained solid was dissolved in a small quantity of MOH