3-azetidinecarboxylic Acid → HCID 69041548, compound

HRID 2040114Notes

Reaction equation

HRID 2040114 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:15]=[CH:16][C:17]=1[O:18][C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=1[C:25]([F:28])([F:27])[F:26])[CH:6]=[C:7]1[S:11][C:10](SC)=[N:9][C:8]1=[O:14].[NH:29]1[CH2:32][CH:31]([C:33]([OH:35])=[O:34])[CH2:30]1>CN(C=O)C>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:15]=[CH:16][C:17]=1[O:18][C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=1[C:25]([F:26])([F:28])[F:27])[CH:6]=[C:7]1[S:11][C:10]([N:29]2[CH2:32][CH:31]([C:33]([OH:35])=[O:34])[CH2:30]2)=[N:9][C:8]1=[O:14]

Participants

4

Reactant 2

HCID 931923-azetidinecarboxylic AcidHCID 69044440HCID 69044440, compound

Product 1

HCID 69041548HCID 69041548, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

was prepared from 5-[3-Methoxy-4-(2-trifluoromethyl-phenoxy)-benzylidene]-2-methylsulfanyl-thiazol-4-one and azetidine-3-carboxylic acid and substituting MeCN with DMF as described in Example 5C

Sources & evidence

ORD record
ord-668fa627de24441eb3856a078e8e30c3
Source dataset
uspto-grants-2013_11
Patent number
US08580832B2

Reaction notes

Loading…