4-Cyanophenol → HCID 178458439, compound
Reaction equation
[CH2:1]([O:4][C:5]1[C:14](C)=[CH:13][C:8]([C:9]([NH:11][OH:12])=[NH:10])=[CH:7][C:6]=1C)[CH:2]=[CH2:3].OC1C=CC(C#N)=CC=1>>[CH2:1]([O:4][C:5]1[CH:14]=[CH:13][C:8]([C:9]([NH:11][OH:12])=[NH:10])=[CH:7][CH:6]=1)[CH:2]=[CH2:3]Participants
3
Procedure
The title compound is prepared in analogy to 4-allyloxy-N-hydroxy-3,5-dimethyl-benzamidine by allylating commercially available 4-hydroxy-benzonitrile followed by transforming the nitrile to the hydroxyamidine; LC-MS: tR=0.59 min, [M+1]+=193.58.
Sources & evidence
- ORD record
- ord-a8d4b80593dd464a83c3694faaf47425
- Source dataset
- uspto-grants-2013_11
- Patent number
- US08580824B2
Reaction notes
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