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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2040821Generated: October 29, 2026

Ammonia → HCID 59234740, compound

https://huagongshe.com/reaction/2040821

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniaHCID 222—
ReactantHCID 86639883HCID 86639883—
SolventMethanolHCID 887—
ProductHCID 59234740HCID 59234740—

Reaction Steps

(S)-2-ethyl-4-[3-(3-ethyl-5-methyl-4-oxiranylmethoxy-phenyl)-[1,2,4]oxadiazol-5-yl]-6-methyl-pyridine is treated with ammonia in MeOH as described in Example 46 step b) to give (R)-1-amino-3-{2-ethyl-4-[5-(2-ethyl-6-methyl-pyridin-4-yl)-[1,2,4]oxadiazol-3-yl]-6-methyl-phenoxy}-propan-2-ol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08580824B2
Source datasetuspto-grants-2013_11
ORD IDord-0f2533466d32475bb7fcf7afb8243485
Source noteuspto-grants-2013_11