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HRID2040845

反应详情

EQUATION

反应方程式

HRID 2040845 的结构方程式

REACTANTS

反应物

2
反应SMILES：Cc1cccc(Br)n1
HCID79205

2-Bromo-6-methylpyridine

C6H6BrN

反应SMILES：C=C1CCN(c2nc(C)ccc2[N+](=O)[O-])CC1
HCID57493810

未命名化合物

PRODUCTS

产物

1
反应SMILES：Cc1ccc([N+](=O)[O-])c(N2CCC3(CC2)CC(C#Cc2ccccn2)=NO3)n1
HCID56645678

未命名化合物

收率 49.6%

PROCEDURE

实验过程

The title product was prepared replacing 2-iodopyridine for 2-bromo-6-methylpyridine following the procedure reported above for the compound of Example 3. Purification of the residue by automated flash liquid chromatography (Horizon®TM-Biotage) (Petroleum Ether-EtOAc gradient from 9:1 to 4:6). Yield: 49.6%.

WORKUP

后处理

  1. customPurification of the residue by automated flash liquid chromatography (Horizon®TM-Biotage) (Petroleum Ether-EtOAc gradient from 9:1 to 4:6)