HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Phenylethynyl)-1-oxa-2,8-diazaspiro[4.5]dec-2-ene → 7-(Phenylethynyl)-5-oxa-2,6-diazaspiro[3.4]oct-6-ene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Phenylethynyl)-1-oxa-2,8-diazaspiro[4.5]dec-2-ene | HCID 57493808 | — |
| Reactant | tert-Butyl 7-(phenylethynyl)-5-oxa-2,6-diazaspiro[3.4]oct-6-ene-2-carboxylate | HCID 57493839 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 7-(Phenylethynyl)-5-oxa-2,6-diazaspiro[3.4]oct-6-ene | HCID 57493840 | 100% |
Reaction Steps
The title compound was synthesized following the method reported for Compound 1c, substituting Compound 1b with Compound 38a and running the reaction in chloroform. The crude brownish oily residue was used without further purification in the next reaction step. Yield: 100%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08580962B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-f1dacd33753e403ba57171374c9860c1 |
| Source note | uspto-grants-2013_11 |