反应详情

The title compound was prepared following the method reported herein for Compound 31a. As starting material diethyl 4-oxocyclohexane-1,1-dicarboxylate replaced 1,4-dioxaspiro[4.5]decan-8-one. After the usual work-up procedure the residue was purified by means of automated flash chromatography (SP01®TM-Biotage; gradient Petroleum Ether-EtOAc from 1:0 to 8:2) to give the title compound as a colorless oil. Yield: 88.1%.

1. customThe title compound was prepared
2. customAfter the usual work-up procedure the residue was purified by means of automated flash chromatography (SP01®TM-Biotage; gradient Petroleum Ether-EtOAc from 1:0 to 8:2)