huagongshe.com
HRID2040899

反应详情

EQUATION

反应方程式

HRID 2040899 的结构方程式

REACTANTS

反应物

3
反应SMILES：O=C1CCC2(CC1)OCCO2
HCID567415

1,4-Dioxaspiro[4.5]decan-8-one

C8H12O3

反应SMILES：C=C1CCC2(CC1)OCCO2
HCID10953743

8-Methylene-1,4-dioxaspiro[4.5]decane

C9H14O2

反应SMILES：O=C1COCc2ccccc21
HCID12339648

1H-2-Benzopyran-4(3H)-one

C9H8O2

PRODUCTS

产物

1
反应SMILES：C=C1COCc2ccccc21
HCID11171052

3,4-Dihydro-4-methylene-1H-2-benzopyran

C10H10O

收率 69.8%

PROCEDURE

实验过程

This intermediate was prepared following the procedure described Compound 31a. As starting material isochroman-4-one replaced 1,4-dioxaspiro[4.5]decan-8-one. After the usual work-up procedure the residue was purified by means of automated flash chromatography (SP01®TM-Biotage; gradient Petroleum Ether-EtOAc from 1:0 to 0:1) to give the title compound as a colorless oil. Yield: 69.8%.

WORKUP

后处理

  1. customThis intermediate was prepared
  2. customAfter the usual work-up procedure the residue was purified by means of automated flash chromatography (SP01®TM-Biotage; gradient Petroleum Ether-EtOAc from 1:0 to 0:1)