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HRID2040902

反应详情

EQUATION

反应方程式

HRID 2040902 的结构方程式

REACTANTS

反应物

2
结构：CN1CCN(C(=O)Cl)CC1
HCID3016935

4-methylpiperazine-1-carbonyl Chloride

C6H11ClN2O

结构：CN1CCN(C(=O)N2CCC3(CC(C#Cc4cccc(Cl)c4)=NO3)C2)CC1
HCID56644861

未命名化合物

PRODUCTS

生成物

1
结构：O=C(N1CCCC1)N1CCC2(CC(C#Cc3cccc(Cl)c3)=NO2)C1
HCID57493783

未命名化合物

收率 72.8%

PROCEDURE

实验过程

The title compound was synthesized using the method described for the compound of Example 104, replacing 1-pyrrolidincarbonyl chloride for 4-methyl-1-piperazinecarbonyl chloride. After the usual work-up procedure, the crude was purified by means of automated flash chromatography (SP01®TM-Biotage; CHCl3-1.4N methanolic ammonia 100:0.5) to afford an ivory solid. Yield: 72.8%.

WORKUP

后处理

  1. customAfter the usual work-up procedure, the crude was purified by means of automated flash chromatography (SP01®TM-Biotage; CHCl3-1.4N methanolic ammonia 100:0.5)
  2. customto afford an ivory solid