Potassium Hydroxide → 2-vinylaniline

HRID 2041815Notes

Reaction equation

HRID 2041815 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][CH2:9]O.[OH-].[K+]>>[CH:8]([C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=1[NH2:1])=[CH2:9]

Participants

3

Reactant 2

HCID 14797Potassium HydroxideHCID 79282o-Aminophenethyl alcohol

Product 1

HCID 103516892-vinylanilineYield 48.4%

Conditions

Temperature
200 °C

Procedure

A mixture of 2-(2-aminophenyl)ethanol (5 g, 36.4 mmol) and KOH (2.0 g, 36.4 mmol) was heated to 200° C. for 4 h. After cooling, the mixture was distilled under vacuum to yield 2.1 g of product.

Workup

  1. temperatureAfter cooling
  2. distillationthe mixture was distilled under vacuum

Sources & evidence

ORD record
ord-414c03b150fa49bfae793ae5ecc549b4
Source dataset
uspto-grants-2013_11
Patent number
US08586203B2

Reaction notes

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