HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Dichloroacetone → HCID 66995415, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Dichloroacetone | HCID 10793 | — |
| Reactant | 4-Bromo-1,2-difluorobenzene | HCID 67675 | — |
| Reactant | HCID 178506865 | HCID 178506865 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 66995415 | HCID 66995415 | — |
Reaction Steps
Preparation according to Preparation 1: 1-bromo-3,4-difluorobenzene (5 g, 25.9 mmol), dry diethyl ether (100 mL), n-hexyllithium (2.3 M in hexane, 11.2 ml, 25.9 mmol) and 1,3-dichloroacetone (3.29 g, 25.9 mol). Yield: 4.54 g (73%). MS m/z (rel. intensity, 70 eV) 241 (M+, 1), 193 (32), 191 (bp), 141 (14), 127 (64).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08586572B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-0450c214bd2547028088ae775734d7ea |
| Source note | uspto-grants-2013_11 |