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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2041939Generated: October 30, 2026

2-Methyl-3-nitro-6-(pyrrolidin-1-yl)pyridine → 2-Methyl-6-(pyrrolidin-1-yl)pyridin-3-amine

https://huagongshe.com/reaction/2041939

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-3-nitro-6-(pyrrolidin-1-yl)pyridineHCID 57431522—
CatalystPalladiumHCID 23938—
Product2-Methyl-6-(pyrrolidin-1-yl)pyridin-3-amineHCID 5743152372.4%

Reaction Steps

The process is carried out according to the method described in step 5.2, using 0.55 g (2.65 mmol) of 2-methyl-6-(pyrrolidin-1-yl)-3-nitropyridine, prepared in step 9.1, and 0.1 g of 10% palladium-on-charcoal. 0.34 g of the expected product is thus obtained, which product will be used as it is in the rest of the synthesis.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08586573B2
Source datasetuspto-grants-2013_11
ORD IDord-a8094ab3430f4a3ca4f722388b6b2067
Source noteuspto-grants-2013_11