HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methyl-3-nitro-6-(pyrrolidin-1-yl)pyridine → 2-Methyl-6-(pyrrolidin-1-yl)pyridin-3-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methyl-3-nitro-6-(pyrrolidin-1-yl)pyridine | HCID 57431522 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | 2-Methyl-6-(pyrrolidin-1-yl)pyridin-3-amine | HCID 57431523 | 72.4% |
Reaction Steps
The process is carried out according to the method described in step 5.2, using 0.55 g (2.65 mmol) of 2-methyl-6-(pyrrolidin-1-yl)-3-nitropyridine, prepared in step 9.1, and 0.1 g of 10% palladium-on-charcoal. 0.34 g of the expected product is thus obtained, which product will be used as it is in the rest of the synthesis.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08586573B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-a8094ab3430f4a3ca4f722388b6b2067 |
| Source note | uspto-grants-2013_11 |