HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(3-Azabicyclo[3.1.0]hex-3-yl)-5-nitropyridine → 2-(3-Azabicyclo[3.1.0]hex-3-yl)-5-aminopyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(3-Azabicyclo[3.1.0]hex-3-yl)-5-nitropyridine | HCID 57431530 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | 2-(3-Azabicyclo[3.1.0]hex-3-yl)-5-aminopyridine | HCID 57431531 | 0.1% |
Reaction Steps
The process is carried out according to the method used in example 5.2, using 0.2 g (0.97 mol) of 2-(3-azabicyclo[3.1.0]hex-3-yl)-5-nitropyridine, described in step 12.1, and 0.5 g of 10% palladium-on-charcoal. 0.1 g of the expected product is thus isolated, which product will be used as it is in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08586573B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-813bc2bd260a4ff4bb37c83f7e9b9058 |
| Source note | uspto-grants-2013_11 |