HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-4-chloropyrimidine → HCID 67252394, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-4-chloropyrimidine | HCID 223332 | — |
| Reactant | 3-Amino-4-fluorophenol | HCID 13519180 | — |
| Product | HCID 67252394 | HCID 67252394 | 59.9% |
Reaction Steps
Using a procedure analogous to Example A3, 3-amino-4-fluorophenol (491 mg, 3.86 mmol) and 4-chloropyrimidin-2-amine (500 mg, 3.86 mmol) were combined to give 4-(3-amino-4-fluorophenoxy)pyrimidin-2-amine (509 mg, 59% yield). MS (ESI) m/z: 221.0 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08586565B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-4e41a0186e204bb7bee510d3b8f50d4f |
| Source note | uspto-grants-2013_11 |