Toluene → 1-(4-fluorophenyl)-6-[3-(pyrrolidin-1-yl)propoxy]-3,4-dihydroquinolin-2(1H)-one
Reaction equation
[C:29](=[O:30])([O-:31])[O-:32].[CH3:35][c:36]1[cH:37][cH:38][cH:39][cH:40][cH:41]1.[CH:42]([Cl:43])([Cl:44])[Cl:45].[Cs+:33].[Cs+:34].[Cu:46]([I:47])[I:48].[F:21][c:22]1[cH:23][cH:24][c:25]([I:28])[cH:26][cH:27]1.[N:1]1([CH2:6][CH2:7][CH2:8][O:9][c:10]2[cH:11][c:12]3[c:17]([cH:18][cH:19]2)[NH:16][C:15](=[O:20])[CH2:14][CH2:13]3)[CH2:2][CH2:3][CH2:4][CH2:5]1>>[N:1]1([CH2:6][CH2:7][CH2:8][O:9][c:10]2[cH:11][c:12]3[c:17]([cH:18][cH:19]2)[N:16]([c:25]2[cH:24][cH:23][c:22]([F:21])[cH:27][cH:26]2)[C:15](=[O:20])[CH2:14][CH2:13]3)[CH2:2][CH2:3][CH2:4][CH2:5]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-fdb1ef84179f43a7a6024f050504c73f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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