HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-Difluoro-4-iodobenzene → 2-tert-Butyl-6-(3,4-difluoro-phenylethynyl)-pyrazolo[1,5-a]pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-Difluoro-4-iodobenzene | HCID 2724444 | — |
| Reactant | 2-tert-Butyl-6-ethynyl-pyrazolo[1,5-a]pyrimidine | HCID 58316702 | — |
| Product | 2-tert-Butyl-6-(3,4-difluoro-phenylethynyl)-pyrazolo[1,5-a]pyrimidine | HCID 53247332 | — |
Reaction Steps
The title compound, light yellow solid, MS: m/e=312.2 (M+H+), can be prepared in accordance with the general method of example 1 from 2-tert-butyl-6-ethynyl-pyrazolo[1,5-a]pyrimidine (example 21, step 2) and 1,2-difluoro-4-iodobenzene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08586581B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-05151dc397894cc0871cfad246f6818b |
| Source note | uspto-grants-2013_11 |