Potassium Carbonate → HCID 58316701, compound

Participants

Reaction Steps

A solution of acetic acid 2-(6-iodo-[1,2,4]triazolo[1,5-a]pyridin-2-yl)-2-methyl-propyl ester (example 40, step 6) (750 mg, 2.09 mmol) and K2CO3 (576 mg, 4.18 mmol, 2 equiv.) in MeOH (8 ml) was stirred at 25° C. for 2 hours. The solvent was evaporated and the resulting crude product was purified by column chromatography. The desired 2-(6-iodo-[1,2,4]triazolo[1,5-a]pyridin-2-yl)-2-methyl-propan-1-ol (662 mg, 91% yield) was obtained as a white solid, MS: m/e=318.0 (M+H+).

Provenance & Evidence