HRID2042226

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID14479558

未命名化合物

结构：CNS(=O)(=O)c1cccc(-c2csc3cnc(N)nc23)c1

HCID67120139

Benzenesulfonamide, 3-(2-aminothieno[3,2-d]pyrimidin-7-yl)-N-methyl-

C13H12N4O2S2

PRODUCTS

生成物

结构：CNS(=O)(=O)c1cccc(-c2csc3cnc(Nc4cc(N5CCN(CCO)CC5)nc(C)n4)nc23)c1

HCID52931896

未命名化合物

收率 53.7%

PROCEDURE

实验过程

3-(2-(6-(4-(2-Hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-ylamino)thieno[3,2-d]pyrimidin-7-yl)-N-methylbenzenesulfonamide (18 mg, 53% yield) was prepared in the same manner as Step 10 of Example 1 using 3-(2-aminothieno[3,2-d]pyrimidin-7-yl)-N-methylbenzenesulfonamide (20 mg, 0.062 mmol) and 2-(4-(6-chloro-2-methylpyrimidin-4-yl)piperazin-1-yl)ethanol (17 mg, 0.062 mmol).