HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloropropanesulphonyl chloride → 3-Chloro-N-(3-(2-chloro thieno[3,2-d]pyrimidin-7-yl)phenyl)propane-1-sulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloropropanesulphonyl chloride | HCID 15410 | — |
| Reactant | 3-(2-Chlorothieno[3,2-d]pyrimidin-7-yl)benzenamine | HCID 86673214 | — |
| Product | 3-Chloro-N-(3-(2-chloro thieno[3,2-d]pyrimidin-7-yl)phenyl)propane-1-sulfonamide | HCID 86673226 | 78.5% |
Reaction Steps
3-Chloro-N-(3-(2-chloro thieno[3,2-d]pyrimidin-7-yl)phenyl)propane-1-sulfonamide (240 mg, 78% yield) was prepared in the same manner as Step 7 of Example 1 using 3-(2-chlorothieno[3,2-d]pyrimidin-7-yl)benzenamine (200 mg, 0.76 mmol) and 3-chloropropane-1-sulfonyl chloride (145 mg, 0.84 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08586580B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-a9052f787be24fdfaedfd9c938223db5 |
| Source note | uspto-grants-2013_11 |