Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2042491Generated: November 1, 2026

Acetic Acid → HCID 178474982, compound

https://huagongshe.com/reaction/2042491

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
ReactantHCID 178447389HCID 178447389—
ProductHCID 178474982HCID 178474982—

Reaction Steps

The title compound, white solid (96 mg, 83%), MS (ISP) m/z=387.4 [(M+H)+], mp 217.5° C., was prepared in accordance with the general method of example 32 from trans-4-{2-[4-(6-methyl-2,3-dihydro-furo[3,2-c]pyridin-4-yl)-piperazin-1-yl]-ethyl}-cyclohexylamine trihydrochloride (intermediate E) (136 mg, 0.3 mmol) and acetic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08586579B2
Source datasetuspto-grants-2013_11
ORD IDord-d6db5e0b51a340f5826efb72b252326e
Source noteuspto-grants-2013_11