Tetrahydropyran-4-ylacetic acid → HCID 178430614, compound

Participants

Reaction Steps

The title compound, white solid (52 mg, 74%), MS (ISP) m/z=471.6 [(M+H)+], mp 199° C., was prepared in accordance with the general method of example 32 from trans-4-{2-[4-(7-methyl-2,3-dihydro-furo[3,2-c]pyridin-4-yl)-piperazin-1-yl]-ethyl}-cyclohexylamine trihydrochloride (intermediate G) (68.1 mg, 0.15 mmol) and tetrahydropyran-4-yl-acetic acid.

Provenance & Evidence