HCID 59652062, compound → HCID 59651940, compound

HRID 2042597Notes

Reaction equation

HRID 2042597 reaction equation
[CH2:1]([O:3][C:4](=[O:25])[CH2:5][C:6]([CH3:24])([CH3:23])[C:7]([C:9]1[CH:14]=[CH:13][C:12]([O:15]CC2C=CC=CC=2)=[CH:11][CH:10]=1)=[O:8])[CH3:2]>CO.[Pd]>[CH2:1]([O:3][C:4](=[O:25])[CH2:5][C:6]([CH3:24])([CH3:23])[C:7]([C:9]1[CH:10]=[CH:11][C:12]([OH:15])=[CH:13][CH:14]=1)=[O:8])[CH3:2]

Participants

4

Reactant 1

HCID 59652062HCID 59652062, compound

Product 1

HCID 59651940HCID 59651940, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

The product from step 1 (1.25 g, 3.83 mmol) and 10% Pd/C (0.3 g) in MeOH (50 mL) was hydrogenated on a Parr apparatus until TLC indicated completion of the reaction. The mixture was filtered, concentrated to an oil and used directly in the next step; MS m/z 204 (M-OMe).

Workup

  1. customcompletion of the reaction
  2. filtrationThe mixture was filtered
  3. concentrationconcentrated to an oil

Sources & evidence

ORD record
ord-545c26808be14429afabb4d728dbb7e6
Source dataset
uspto-grants-2013_11
Patent number
US08586588B2

Reaction notes

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