Sodium ion → 2-Pyrazinamine, 5-(3-methoxyphenyl)-

HRID 204269Notes

Reaction equation

HRID 204269 reaction equation
[CH2:26]([CH2:27][O:28][CH3:29])[O:30][CH3:31].[CH3:1][O:2][c:3]1[cH:4][c:5]([B:9]([OH:10])[OH:11])[cH:6][cH:7][cH:8]1.[NH2:12][c:13]1[n:14][cH:15][c:16]([Br:19])[n:17][cH:18]1.[Na+:20].[Na+:21].[O-:22][C:23](=[O:24])[O-:25].[OH2:73].[Pd:32]([Cl:33])[Cl:34].[c:35]1([P:36]([c:37]2[cH:38][cH:39][cH:40][cH:41][cH:42]2)[c:43]2[cH:44][cH:45][cH:46][cH:47][cH:48]2)[cH:49][cH:50][cH:51][cH:52][cH:53]1.[c:54]1([P:55]([c:56]2[cH:57][cH:58][cH:59][cH:60][cH:61]2)[c:62]2[cH:63][cH:64][cH:65][cH:66][cH:67]2)[cH:68][cH:69][cH:70][cH:71][cH:72]1>>[CH3:1][O:2][c:3]1[cH:4][c:5](-[c:16]2[cH:15][n:14][c:13]([NH2:12])[cH:18][n:17]2)[cH:6][cH:7][cH:8]1

Participants

9

Reactant 8

HCID 923Sodium ion2×HCID 962WaterHCID 80711,2-DimethoxyethaneHCID 11776Triphenylphosphine2×HCID 19660Carbonate IonHCID 24290Palladium ChlorideHCID 5995392-Amino-5-bromopyrazineHCID 2734370(3-Methoxyphenyl)boronic acid

Product 1

HCID 218973522-Pyrazinamine, 5-(3-methoxyphenyl)-

Sources & evidence

ORD record
ord-486ca24c94ea462ca26f98283ba70590
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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