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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2042775Generated: November 2, 2026

8-methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-amine → N-(2-Benzo[b]thienylethyl)-N-(8-methoxytetralin-2-yl)-N-propylamine

https://huagongshe.com/reaction/2042775

Reaction equation

Participants

RoleNameHCIDCharge
Reactant8-methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-amineHCID 12741417—
Reactant2-(1-Benzothiophen-2-yl)acetic acidHCID 12765065—
ProductN-(2-Benzo[b]thienylethyl)-N-(8-methoxytetralin-2-yl)-N-propylamineHCID 67252230—

Reaction Steps

Synthesis works according to the preparation of A4-1 or A4-4 when using N-(8-methoxytetralin-2-yl)-N-propylamine (A2-1: R═OMe) and 2-benzo[b]thienyl acetic acid (A3-10: R═OMe, Cy=2-benzo[b]thienyl) (purchasable from Rare Chemicals, Kiel (Germany); order number: GT HW 0344) and subsequent reaction according to the synthesis of A5-1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08586603B2
Source datasetuspto-grants-2013_11
ORD IDord-5b07ce2d562a4cbbbae31e8b7cde5637
Source noteuspto-grants-2013_11