HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzo[b]thiophene-3-acetic acid → N-(3-Benzo[b]thienylethyl)-N-(8-methoxytetralin-2-yl)-N-propylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzo[b]thiophene-3-acetic acid | HCID 70799 | — |
| Reactant | 8-methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-amine | HCID 12741417 | — |
| Product | N-(3-Benzo[b]thienylethyl)-N-(8-methoxytetralin-2-yl)-N-propylamine | HCID 67250552 | — |
Reaction Steps
Synthesis works according to the preparation of A4-1 or A4-4 when using N-(8-methoxytetralin-2-yl)-N-propylamine (A2-1: R═OMe) and 3-benzo[b]thienyl acetic acid (A3-11: R═OMe, Cy=3-benzo[b]thienyl) (purchasable from Alfa Aesar, Karlsruhe (Germany); order number: LO 5855 or Maybridge, Tintagel, Cornwall (UK); order number: S11080) and subsequent reaction according to the synthesis of A5-1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08586603B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-3a2d3a0c18644197992207d9724f0f62 |
| Source note | uspto-grants-2013_11 |