反应详情

trans-4-Trifluoromethyl-cyclohexanecarboxylic acid (2.0 g, 10.2 mmol) is stirred in thionyl chloride (30 mL) for 1 h at reflux. The reaction mixture is concentrated and used directly in the next step without further purification.

1. temperatureat reflux
2. concentrationThe reaction mixture is concentrated
3. customused directly in the next step without further purification