HuagongsheHuagongshe Chemistry Print Report · For research reference only
Nitric Acid → HCID 178523751, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Nitric Acid | HCID 944 | — |
| Reactant | HCID 178523749 | HCID 178523749 | — |
| Solvent | Sulfuric Acid | HCID 1118 | — |
| Product | HCID 178523751 | HCID 178523751 | — |
Reaction Steps
The sub-title compound is prepared from 6-chloro-2-(2,2-difluoro-ethoxy)-N-(trans-4-trifluoromethyl-cyclohexyl)-nicotinamide (7.2 g, 18.6 mmol) and fuming HNO3 (20 mL) in conc. H2SO4 (40 mL) in analogy with example 1c.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08586604B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-36538725116740bca7b2ab0933889b63 |
| Source note | uspto-grants-2013_11 |