HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → HCID 178482444, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | HCID 178523750 | HCID 178523750 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 178482444 | HCID 178482444 | — |
Reaction Steps
The sub-title compound is prepared from 6-chloro-2-(2-fluoro-ethoxy)-5-nitro-N-(trans-4-trifluoromethyl-cyclohexyl)-nicotinamide (1.00 g, 2.30 mmol) and methylamine (2 M in THF; 2.75 mL, 5.50 mmol) in THF (15 mL) in analogy with method described in example 1d.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08586604B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-f58cc54b03fe48dbb495345c05567c7a |
| Source note | uspto-grants-2013_11 |