HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 178508978, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | HCID 178523750 | HCID 178523750 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 178508978 | HCID 178508978 | — |
Reaction Steps
The sub-title compound is prepared from 6-chloro-2-(2-fluoro-ethoxy)-5-nitro-N-(trans-4-trifluoromethyl-cyclohexyl)-nicotinamide (1.30 g, 2.98 mmol) and conc. ammonia (0.90 mL, 14.92 mmol) in THF (30 mL) in analogy with method described in example 3c.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08586604B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-f03129e5112b4400964db7223ec90149 |
| Source note | uspto-grants-2013_11 |