HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylcarbodiimide → HCID 178447328, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylcarbodiimide | HCID 12734 | — |
| Reactant | N-(2-fluoro-4-chloro-3-isothiocyanato-benzyl)-2,2-dimethyl-propionamide | HCID 56840194 | — |
| Reactant | HCID 178507778 | HCID 178507778 | — |
| Product | HCID 178447328 | HCID 178447328 | — |
Reaction Steps
The title compound is prepared from N-(2-fluoro-4-chloro-3-isothiocyanato-benzyl)-2,2-dimethyl-propionamide (55 mg, 0.18 mmol) and 5,6 diamino-2-(2,2-difluoro-ethoxy)-N-(trans-4-trifluoromethyl-cyclohexyl)-nicotinamide (70 mg, 0.18 mmol) with DIC in analogy to examples 8a/8b.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08586604B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-232aa0d989f7445bae9c7d500bbf7414 |
| Source note | uspto-grants-2013_11 |