Adams' catalyst → 5-Chloro-6-(tetrahydro-furan-3-yl)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[cH:11][c:12]([C:18]3=[CH:22][CH2:21][O:20][CH2:19]3)[c:13]([Cl:17])[cH:14][c:15]2[CH2:16]1.[Pt:23](=[O:24])=[O:25]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[cH:11][c:12]([CH:18]3[CH2:19][O:20][CH2:21][CH2:22]3)[c:13]([Cl:17])[cH:14][c:15]2[CH2:16]1Participants
3
Sources & evidence
- ORD record
- ord-05881a9164e744a58b4d2980c8b3e1d4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
Loading…