HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 16067939, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 4-Chlorobenzoic Acid | HCID 6318 | — |
| Reactant | 1-Azatricyclo[3.3.1.1,3,7]decan-4-amine hydrochloride | HCID 67152122 | — |
| Product | HCID 16067939 | HCID 16067939 | — |
Reaction Steps
Prepared from (4r)-1-azatricyclo[3.3.1.13,7]dec-4-ylamine hydrochloride and 4-chlorobenzoic acid (Aldrich) according to method A; yield 29 mg, 0.07 mmol (33%): 1H NMR (300 MHz, methanol-d4) δ 2.06-2.30 (m, 5H), 2.45 (s, 2H), 3.48 (d, J=12 Hz, 2 H), 3.55 (s, 2H), 3.80 (d, J=12 Hz, 2H), 4.25 (s, 1H), 7.49 (d, J=9 Hz, 2H), 7.86 (d, J=9 Hz, 2H); MS (DCI/NH3) m/z 291 (M+H)+; Anal. C16H19Cl2N2O.HCl.0.45HCl: C, H, N.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08586746B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-914122871a7d45a3ae46b88bab0c3b5d |
| Source note | uspto-grants-2013_11 |