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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2043976Generated: October 29, 2026

{2-[3-Cyclopentylmethyl-3-(4-methanesulfonyl-phenyl)-ureido]thiazol-4-yl}-acetic acid → HCID 67050264, compound

https://huagongshe.com/reaction/2043976

Reaction equation

Participants

RoleNameHCIDCharge
Reactant{2-[3-Cyclopentylmethyl-3-(4-methanesulfonyl-phenyl)-ureido]thiazol-4-yl}-acetic acidHCID 57668194—
ReactantN-(Cyclopentylmethyl)-3-fluoro-4-methoxyanilineHCID 61343915—
Reactant2-Amino-thiazol-5-ylsulfanylacetic acid ethyl esterHCID 67050212—
Reactant{2-[3-Cyclopentylmethyl-3-(3-fluoro-4-methoxy-phenyl)-ureido]-thiazol-5-ylsulfanyl}-acetic acid ethyl esterHCID 86629925—
ProductHCID 67050264HCID 67050264—

Reaction Steps

The title compound was prepared via {2-[3-cyclopentylmethyl-3-(3-fluoro-4-methoxy-phenyl)ureido]-thiazol-5-ylsulfanyl}-acetic acid ethyl ester in a similar manner as described for the synthesis of {2-[3-cyclopentylmethyl-3-(4-methanesulfonyl-phenyl)-ureido]-thiazol-4-yl}-acetic acid, using cyclopentylmethyl-(3-fluoro-4-methoxy-phenyl)-amine and (2-amino-thiazol-5-ylsulfanylacetic acid ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08586614B2
Source datasetuspto-grants-2013_11
ORD IDord-dfd478175ca1461cbb9a1e0293eeb872
Source noteuspto-grants-2013_11