HCID 67236046, compound → HCID 58320701, compound

HRID 2044032Notes

Reaction equation

HRID 2044032 reaction equation
CC1(C)[O:6][C:5](=[CH:7][C:8](=[O:13])[C:9]([F:12])([F:11])[F:10])[CH2:4][O:3]1>O>[OH:13][C:8]1([C:9]([F:10])([F:11])[F:12])[O:3][CH2:4][C:5](=[O:6])[CH2:7]1

Participants

3

Reactant 1

HCID 67236046HCID 67236046, compound

Product 1

HCID 58320701HCID 58320701, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
20 °C

Procedure

A mixture of 3-(2,2-dimethyl-1,3-dioxolan-4-ylidene)-1,1,1-trifluoroacetone (5.21 g, 24.8 mmol) and 20 ml water was stirred at 20° C. for 24 hours. The volatile components were removed under a reduced pressure of 20 mbar. The product was extracted with dichloromethane and the organic phase was dried over MgSO4 and concentrated. The precipitate was purified by crystallization from toluene.

Workup

  1. customThe volatile components were removed under a reduced pressure of 20 mbar
  2. extractionThe product was extracted with dichloromethane
  3. dry with materialthe organic phase was dried over MgSO4
  4. concentrationconcentrated
  5. customThe precipitate was purified by crystallization from toluene

Sources & evidence

ORD record
ord-4b304461a54b4d569b736a2945d135bc
Source dataset
uspto-grants-2013_11
Patent number
US08586753B2

Reaction notes

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