反应详情

温度

100 °C

To a solution of EXAMPLE 512C (1.6 g) and pyridinium p-toluenesulfonate (1.2 g) in acetone (10 mL) was added water (2 mL) and the mixture was stirred in a CEM Discover microwave reactor at 100° C. for 10 minutes. The mixture was diluted with dichloromethane (300 mL) and washed with aqueous NaHCO3, water, brine and dried over Na2SO4. Filtration and evaporation of the solvent gave the crude product.

1. washwashed with aqueous NaHCO3, water, brine
2. dry with materialdried over Na2SO4
3. filtrationFiltration and evaporation of the solvent