Dimethyl Sulfoxide → tert-Butyl (2-((5-cyanopyridin-2-yl)amino)ethyl)carbamate

HRID 204576Notes

Reaction equation

HRID 204576 reaction equation
[C:10](=[O:11])([O:12][C:13]([CH3:14])([CH3:15])[CH3:16])[NH:17][CH2:18][CH2:19][NH2:20].[C:21](=[O:22])([O-:23])[O-:24].[CH3:27][S:28]([CH3:29])=[O:30].[CH3:32][CH2:33][O:34][C:35](=[O:36])[CH3:37].[Cl:1][c:2]1[n:3][cH:4][c:5]([C:6]#[N:7])[cH:8][cH:9]1.[K+:25].[K+:26].[OH2:31]>>[c:2]1([NH:20][CH2:19][CH2:18][NH:17][C:10](=[O:11])[O:12][C:13]([CH3:14])([CH3:15])[CH3:16])[n:3][cH:4][c:5]([C:6]#[N:7])[cH:8][cH:9]1

Participants

8

Reactant 7

HCID 679Dimethyl SulfoxideHCID 813Potassium Cation2×HCID 962WaterHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 187201N-BOC-ethylenediamineHCID 51520946-Chloro-3-pyridinecarbonitrile

Product 1

HCID 47453716tert-Butyl (2-((5-cyanopyridin-2-yl)amino)ethyl)carbamate

Sources & evidence

ORD record
ord-cc163b025bcd4c1d8ffd5fca483976a2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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