Piperazine → HCID 59606520, compound

HRID 2045808Notes

Reaction equation

HRID 2045808 reaction equation
[Cl:1][C:2]1[N:3]=[N:4][C:5]([Cl:9])=[CH:6][C:7]=1Cl.[NH:10]1[CH2:15][CH2:14][NH:13][CH2:12][CH2:11]1>C(O)C>[Cl:1][C:2]1[N:3]=[N:4][C:5]([Cl:9])=[CH:6][C:7]=1[N:10]1[CH2:15][CH2:14][NH:13][CH2:12][CH2:11]1

Participants

4

Reactant 2

HCID 4837PiperazineHCID 951233,4,6-Trichloropyridazine

Product 1

HCID 59606520HCID 59606520, compoundYield 61.2%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

18 g 3,4,6-trichloro-pyridazine and 34 g piperazine are suspended in 100 ml of ethanol and stirred for 30 minutes at ambient temperature. The precipitated solid is suction filtered. 500 ml of water are added to the mother liquor and the precipitated product is suction filtered. 14 g product are obtained in the form of a solid. M.p.=111-115° C.

Workup

  1. filtrationfiltered
  2. addition500 ml of water are added to the mother liquor
  3. filtrationfiltered

Sources & evidence

ORD record
ord-29bf644ae6a34df1a230056f8a49f384
Source dataset
uspto-grants-2013_11
Patent number
US08592400B2

Reaction notes

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