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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2046Generated: October 26, 2026

Phosphine oxide, (chloromethyl)dimethyl- → [1-(8-Bromo-3,7-dimethylxanthin-1-yl)methyl]dimethylphosphine Oxide

https://huagongshe.com/reaction/2046

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhosphine oxide, (chloromethyl)dimethyl-HCID 74224—
ReactantHCID 67653895HCID 67653895—
Product[1-(8-Bromo-3,7-dimethylxanthin-1-yl)methyl]dimethylphosphine OxideHCID 19689193—

Reaction Steps

The title substance was prepared from 28 g (0.1 mol) of 8-bromo-3,7-dimethylxanthine sodium salt and chloromethyldimethylphosphine oxide analogously to Example 59 and chromatographed on silica gel.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05728686
Source datasetuspto-grants-1998_03
ORD IDord-ce9a106c829041ce87d64ebe4577218f
Source noteuspto-grants-1998_03