化工社化工社 化学情報印刷レポート · 研究参考用
4-(tert-Butyldimethylsiloxy)phenol → 2-[4-(tert-Butyl-dimethyl-silanyloxy)-phenoxymethyl]-5-(5-fluoro-pyridin-2-yl)-6,7-dihydro-5H-pyrazolo[1,5-a]pyrazin-4-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-(tert-Butyldimethylsiloxy)phenol | HCID 597388 | — |
| 反応物 | 5-(4-fluorophenyl)-2-(p-tolyloxymethyl)-6,7-dihydro-5H-pyrazolo[1,5-a]pyrazin-4-one | HCID 57410027 | — |
| 反応物 | 5-(5-fluoro-pyridin-2-yl)-2-hydroxymethyl-6,7-dihydro-5H-pyrazolo[1,5-a]pyrazin-4-one | HCID 67974173 | — |
| 生成物 | 2-[4-(tert-Butyl-dimethyl-silanyloxy)-phenoxymethyl]-5-(5-fluoro-pyridin-2-yl)-6,7-dihydro-5H-pyrazolo[1,5-a]pyrazin-4-one | HCID 67975993 | — |
反応手順
The compound was prepared from 4-(tert-butyldimethylsiloxy)phenol and 5-(5-fluoro-pyridin-2-yl)-2-hydroxymethyl-6,7-dihydro-5H-pyrazolo[1,5-a]pyrazin-4-one using the method described in the preceding example 55 (5-(4-fluorophenyl)-2-(p-tolyloxymethyl)-6,7-dihydro-5H-pyrazolo[1,5-a]pyrazin-4-one).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08592422B2 |
| 出典データセット | uspto-grants-2013_11 |
| ORD ID | ord-4535b881d23645179d81b4788a0014f7 |
| 出典メモ | uspto-grants-2013_11 |