HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 4-oxo-4,5,6,7-tetrahydropyrazolo(1,5-a)pyrazine-2-carboxylate → 3-Chloro-4-oxo-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyrazine-2-carboxylic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 4-oxo-4,5,6,7-tetrahydropyrazolo(1,5-a)pyrazine-2-carboxylate | HCID 42873667 | — |
| Reactant | 2-(2-tert-Butoxycarbonylamino-ethyl)-5-phenoxymethyl-2H-pyrazole-3-carboxylic acid ethyl ester | HCID 67958224 | — |
| Reactant | diethyl 4-chloro-1H-pyrazole-3,5-dicarboxylate | HCID 67975929 | — |
| Product | 3-Chloro-4-oxo-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyrazine-2-carboxylic acid ethyl ester | HCID 67974601 | — |
Reaction Steps
The compound was prepared from 4-chloro-1H-pyrazole-3,5-dicarboxylic acid diethyl ester and 2-(2-tert-butoxycarbonylamino)ethyl bromide using the methods described in the preceding examples 5 (2-(2-tert-butoxycarbonylamino-ethyl)-5-phenoxymethyl-2H-pyrazole-3-carboxylic acid ethyl ester) and 48 (4,5,6,7-tetrahydro-4-oxo-pyrazolo[1,5-a]pyrazine-2-carboxylic acid ethyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08592422B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-21cb41255c554df89ddab2730b41478d |
| Source note | uspto-grants-2013_11 |