Trifluoroacetic acid → HCID 86660884, compound

Participants

Reaction Steps

A mixture of tert-butyl[(1R,6S)-6-amino-2,2-difluorocyclohexyl]carbamate (5 g, 19.98 mmol) and TFA (6.16 mL, 80 mmol) in dichloromethane (50 mL) was left to stir overnight, and concentrated to afford the title compound as a brown oil. 19F NMR (CDCl3, 564 MHz) −81.07 (s, 6F); −99.7-−100.1 (d, 1F); −111.1-−111.5 (d, 1F).

Provenance & Evidence