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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 204641Generated: October 29, 2026

Water → N-[3,5-bis(trifluoromethyl)benzyl]-2-chloro-N-(3-hydroxypropyl)-4-iodonicotinamide

https://huagongshe.com/reaction/204641

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantDimethylformamideHCID 6228—
ReactantTetrahydrofuranHCID 8028—
ReactantTriethylamineHCID 8471—
ReactantThionyl ChlorideHCID 24386—
Reactant3-(3,5-Bis(trifluoromethyl)benzylamino)propanolHCID 11638019—
Reactant2-Chloro-4-iodonicotinic acidHCID 17750174—
ProductN-[3,5-bis(trifluoromethyl)benzyl]-2-chloro-N-(3-hydroxypropyl)-4-iodonicotinamideHCID 11786369—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-2bff8d4b101c4106ab9ce431f733f15b
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)