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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2046469Generated: October 31, 2026

2-Acetyl-5-(furan-2-yl)cyclohexane-1,3-dione → 2-amino-7-(furan-2-yl)-4-methyl-7,8-dihydroquinazolin-5(6H)-one

https://huagongshe.com/reaction/2046469

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Acetyl-5-(furan-2-yl)cyclohexane-1,3-dioneHCID 5305948—
Reactant2-Amino-7-(4-fluoro-phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-oneHCID 17221208—
Product2-amino-7-(furan-2-yl)-4-methyl-7,8-dihydroquinazolin-5(6H)-oneHCID 2988436—

Reaction Steps

The title compound was prepared from 2-acetyl-5-furan-2-yl-cyclohexane-1,3-dione (321 mg, 1.46 mmol), from stage 1, following the procedure describing the synthesis of 2-amino-7-(4-fluoro-phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one (example 3/a stage 2/3).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08592430B2
Source datasetuspto-grants-2013_11
ORD IDord-7118d695b3a44275b323fc9a20893a2f
Source noteuspto-grants-2013_11